The in silico identification of novel broad-spectrum antidotes for poisoning by organophosphate anti...
The in silico identification of novel broad-spectrum antidotes for poisoning by organophosphate anticholinesterases
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Scope and Contents
Contents
Owing to their potential to cause serious adverse health effects, significant efforts have been made to develop antidotes for organophosphate (OP) anticholinesterases, such as nerve agents. To be optimally effective, antidotes must not only reactivate inhibited target enzymes, but also have the ability to cross the blood–brain barrier (BBB). Progre...
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Full title
The in silico identification of novel broad-spectrum antidotes for poisoning by organophosphate anticholinesterases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11251483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11251483
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ISSN
0920-654X,1573-4951
E-ISSN
1573-4951
DOI
10.1007/s10822-023-00537-x