The cancer-associated secretory phenotype: a new frontier in targeted therapeutics
The cancer-associated secretory phenotype: a new frontier in targeted therapeutics
About this item
Full title
Author / Creator
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
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More information
Scope and Contents
Contents
Tan discusses the cancer-associated secretory phenotypes (CASPs). Somatic mutations activate CASPs by initiating cargo-specific secretory vesicle biogenesis in the Golgi and accelerating anterograde trafficking of secretory vesicles from Golgi to plasma membrane. Embedded within the CASP regulatory network are Golgi-resident protein complexes that...
Alternative Titles
Full title
The cancer-associated secretory phenotype: a new frontier in targeted therapeutics
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11364386
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11364386
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI182652
