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Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation

Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11415291

Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation

About this item

Full title

Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2024-09, Vol.28 (18), p.e70055-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

From haematopoietic stem cells to megakaryocytes (Mks), cells undergo various mechanical forces that affect Mk differentiation, maturation and proplatelet formation. The mechanotransductor PIEZO1 appears to be a natural candidate for sensing these mechanical forces and regulating megakaryopoiesis and thrombopoiesis. Gain‐of‐function mutations of PI...

Alternative Titles

Full title

Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11415291

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11415291

Other Identifiers

ISSN

1582-1838,1582-4934

E-ISSN

1582-4934

DOI

10.1111/jcmm.70055

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