Systematic Evaluation of Regiochemistry and Lipidation of Aryl Trehalose Mincle Agonists
Systematic Evaluation of Regiochemistry and Lipidation of Aryl Trehalose Mincle Agonists
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The Macrophage-Inducible C-type Lectin receptor (Mincle) plays a critical role in innate immune recognition and pathology, and therefore represents a promising target for vaccine adjuvants. Innovative trehalose-based Mincle agonists with improved pharmacology and potency may prove useful in the development of Th17-mediated adaptive immune responses...
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Full title
Systematic Evaluation of Regiochemistry and Lipidation of Aryl Trehalose Mincle Agonists
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11432005
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11432005
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms251810031
