Effects on Iron Metabolism and System Xc− /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jur...
Effects on Iron Metabolism and System Xc− /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jurkat Cells
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Author / Creator
Liu, Nana , Liu, Ge , Li, Qiang , Hu, Yipeng and Wang, Hong
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Prolonged exposure to hydroquinone (HQ), a metabolite of benzene, can cause severe haematologic disorders in humans. However, the mechanism is still unclear. In the present study, we investigated whether HQ can induce haematological diseases through ferroptosis, which is another form of cell death apart from apoptosis. The results showed that HQ in...
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Full title
Effects on Iron Metabolism and System Xc− /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jurkat Cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11436165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11436165
Other Identifiers
ISSN
2305-6304
E-ISSN
2305-6304
DOI
10.3390/toxics12090644