SMYD1 modulates the proliferation of multipotent cardiac progenitor cells derived from human pluripo...
SMYD1 modulates the proliferation of multipotent cardiac progenitor cells derived from human pluripotent stem cells during myocardial differentiation through GSK3β/β-catenin&ERK signaling
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Author / Creator
Chang, Yun , Bai, Rui , Zhang, Yongshuai , Lu, Wen-Jing , Ma, Shuhong , Zhu, Min , Lan, Feng and Jiang, Youxu
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
The histone-lysine N-methyltransferase SMYD1, which is specific to striated muscle, plays a crucial role in regulating early heart development. Its deficiency has been linked to the occurrence of congenital heart disease. Nevertheless, the precise mechanism by which SMYD1 deficiency contributes to congenital heart disease remains unclear.
We est...
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Full title
SMYD1 modulates the proliferation of multipotent cardiac progenitor cells derived from human pluripotent stem cells during myocardial differentiation through GSK3β/β-catenin&ERK signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11462858
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11462858
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-024-03899-7