Disruption of mgrB gene by ISkpn14 sourced from a blaKPC−2 carrying plasmid mediating polymyxin resi...
Disruption of mgrB gene by ISkpn14 sourced from a blaKPC−2 carrying plasmid mediating polymyxin resistance against carbapenem-resistant Klebsiella pneumoniae during treatment: study on the underlying mechanisms
About this item
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Author / Creator
Li, Ziyao , Lei, Zichen , Liu, Xinmeng , Zhang, Feilong , Yang, Xinrui , Wu, Yongli , Li, Chen , Zhao, Jiankang , Zhang, Yulin , Hua, Yanning , Lu, Binghuai and Cao, Bin
Publisher
London: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections poses global challenges, with limited options available for targeted therapy. Polymyxin was been regarded as one of the most important last-resort antimicrobial agents. Many factors could accelerate the resistance evolution of polymyxin. Insertion sequence (IS) inserted into mgrB is the m...
Alternative Titles
Full title
Disruption of mgrB gene by ISkpn14 sourced from a blaKPC−2 carrying plasmid mediating polymyxin resistance against carbapenem-resistant Klebsiella pneumoniae during treatment: study on the underlying mechanisms
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11494788
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11494788
Other Identifiers
ISSN
1471-2180
E-ISSN
1471-2180
DOI
10.1186/s12866-024-03572-2
