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Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions

Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11507603

Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions

About this item

Full title

Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2024-10, Vol.25 (20), p.11099

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Ubiquitin (Ub) signals are recognized and decoded into cellular responses by Ub-receptors, proteins that tether the Ub-binding domain(s) (UBDs) with response elements. Typically, UBDs bind mono-Ub in highly dynamic and weak affinity manners, presenting challenges in identifying and characterizing their binding interfaces. Here, we report the develo...

Alternative Titles

Full title

Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11507603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11507603

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms252011099

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