DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyproto...
DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyprotonated cellular milieu
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English
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With the sensitivity enhancements conferred by dynamic nuclear polarization (DNP), magic angle spinning (MAS) solid state NMR spectroscopy experiments can attain the necessary sensitivity to detect very low concentrations of proteins. This potentially enables structural investigations of proteins at their endogenous levels in their biological conte...
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DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyprotonated cellular milieu
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11572114
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11572114
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ISSN
0925-2738
E-ISSN
1573-5001
DOI
10.1007/s10858-024-00436-9