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DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyproto...

DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyproto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11572114

DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyprotonated cellular milieu

About this item

Full title

DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyprotonated cellular milieu

Journal title

Journal of biomolecular NMR, 2024-03, Vol.78 (2), p.95-108

Language

English

Formats

More information

Scope and Contents

Contents

With the sensitivity enhancements conferred by dynamic nuclear polarization (DNP), magic angle spinning (MAS) solid state NMR spectroscopy experiments can attain the necessary sensitivity to detect very low concentrations of proteins. This potentially enables structural investigations of proteins at their endogenous levels in their biological conte...

Alternative Titles

Full title

DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fullyprotonated cellular milieu

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11572114

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11572114

Other Identifiers

ISSN

0925-2738

E-ISSN

1573-5001

DOI

10.1007/s10858-024-00436-9

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