Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and...
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication
About this item
Full title
Author / Creator
Tanaka, Junichi , Senpuku, Hidenobu , Ogawa, Miho , Yasuhara, Rika , Ohnuma, Shintaro , Takamatsu, Koki , Watanabe, Takashi , Mabuchi, Yo , Nakamura, Shiro , Ishida, Shoko , Sadaoka, Tomohiko , Takaki, Takashi , Shirota, Tatsuo , Shimane, Toshikazu , Inoue, Tomio , Sakai, Takayoshi , Mori, Munemasa , Tsuji, Takashi , Saito, Ichiro and Mishima, Kenji
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Salivary glands act as virus reservoirs in various infectious diseases and have been reported to be targeted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the mechanisms underlying infection and replication in salivary glands are still enigmatic due to the lack of proper in vitro models. Here, we show that human induced...
Alternative Titles
Full title
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication
Authors, Artists and Contributors
Author / Creator
Senpuku, Hidenobu
Ogawa, Miho
Yasuhara, Rika
Ohnuma, Shintaro
Takamatsu, Koki
Watanabe, Takashi
Mabuchi, Yo
Nakamura, Shiro
Ishida, Shoko
Sadaoka, Tomohiko
Takaki, Takashi
Shirota, Tatsuo
Shimane, Toshikazu
Inoue, Tomio
Sakai, Takayoshi
Mori, Munemasa
Tsuji, Takashi
Saito, Ichiro
Mishima, Kenji
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11580836
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11580836
Other Identifiers
ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/s41556-022-01007-6
