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IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathw...

IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathw...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11628342

IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway

About this item

Full title

IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway

Publisher

Australia: Ivyspring International Publisher

Journal title

International journal of biological sciences, 2024-01, Vol.20 (15), p.6146-6161

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher

More information

Scope and Contents

Contents

Tyrosine kinase inhibitors (TKIs), such as sunitinib, have emerged as promising agents in renal cell carcinoma (RCC) treatment, particularly in patients at advanced/metastatic clinical stages. However, acquired resistance to sunitinib is common following prolonged clinical treatment in RCC. Increasing evidence has demonstrated a strong correlation...

Alternative Titles

Full title

IKBKE regulates renal cell carcinoma progression and sunitinib resistance through the RRM2-AKT pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11628342

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11628342

Other Identifiers

ISSN

1449-2288

E-ISSN

1449-2288

DOI

10.7150/ijbs.102666

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