A functional aged human iPSC‐cortical neuron model recapitulates Alzheimer's disease, senescence, an...
A functional aged human iPSC‐cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics
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United States: John Wiley and Sons Inc
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Language
English
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Publisher
United States: John Wiley and Sons Inc
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INTRODUCTION
The degeneration of cortical layers is associated with cognitive decline in Alzheimer's disease (AD). Current therapies for AD are not disease‐modifying, and, despite substantial efforts, research and development for AD has faced formidable challenges. In addition, cellular senescence has emerged as a significant contributor to ther...
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A functional aged human iPSC‐cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11633364
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11633364
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ISSN
1552-5260,1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.14044
