Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung i...
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Acute respiratory distress syndrome (ARDS) is associated with significant morbidity and mortality, and neutrophils are critical to its pathogenesis. Neutrophil activation is closely regulated by inhibitory tyrosine phosphatases including Src homology region 2 domain-containing phosphatase-1 (Shp1). Here, we report that loss of neutrophil Shp1 in mi...
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Full title
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11645157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11645157
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI183161
