Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates...
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
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Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd and European League Against Rheumatism
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Scope and Contents
Contents
ObjectivesMetabolic changes are crucially involved in osteoclast development and may contribute to bone degradation in rheumatoid arthritis (RA). The enzyme aconitate decarboxylase 1 (Acod1) is known to link the cellular function of monocyte-derived macrophages to their metabolic status. As osteoclasts derive from the monocyte lineage, we hypothesi...
Alternative Titles
Full title
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11671873
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11671873
Other Identifiers
ISSN
0003-4967,1468-2060
E-ISSN
1468-2060
DOI
10.1136/ard-2023-224774
