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Network pharmacology and molecular docking to explore mechanisms of clozapine-induced cardiac arrest

Network pharmacology and molecular docking to explore mechanisms of clozapine-induced cardiac arrest

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11684924

Network pharmacology and molecular docking to explore mechanisms of clozapine-induced cardiac arrest

About this item

Full title

Network pharmacology and molecular docking to explore mechanisms of clozapine-induced cardiac arrest

Publisher

Canada: CMA Impact Inc

Journal title

Journal of psychiatry & neuroscience, 2025-01, Vol.50 (1), p.E1-E10

Language

English

Formats

Publication information

Publisher

Canada: CMA Impact Inc

More information

Scope and Contents

Contents

ABSTRACTBackgroundClozapine is superior to all other antipsychotics in treating schizophrenia in terms of its curative efficacy; however, this drug is prescribed only as a last resort in the treatment of schizophrenia, given its potential to induce cardiac arrest. The mechanism of clozapine-induced cardiac arrest remains unclear, so we aimed to elu...

Alternative Titles

Full title

Network pharmacology and molecular docking to explore mechanisms of clozapine-induced cardiac arrest

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11684924

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11684924

Other Identifiers

ISSN

1180-4882,1488-2434

E-ISSN

1488-2434

DOI

10.1503/jpn.240065

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