Neuropathologic and transcriptomic analysis reveals abnormal stress response in sporadic progressive...
Neuropathologic and transcriptomic analysis reveals abnormal stress response in sporadic progressive supranuclear palsy autopsy brain tissue and human iPSC‐derived midbrain organoids
About this item
Full title
Author / Creator
Whitney, Kristen R. , Krassner, Margaret M. , Selecky, Grace A. , Dangoor, Diana K. , De Sanctis, Claudia , Almazan, Victoria Flores , Cervera, Alessandra , Delica, Sean Thomas , Kim, SoongHo , Farrell, Kurt W. , Sharma, Abhijeet , Christie, Thomas D. , Iida, Megan A , Walsh, Hadley A. , Sarrafha, Lily , Parfitt, Gustavo , Walker, Ruth H. , Riboldi, Giulietta M. , Frucht, Steven J. , Ahfeldt, Tim , Zhang, Bin , Pereira, Ana C. , Temple, Sally , Crary, John F. and Song, Won‐min
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
Progressive supranuclear palsy (PSP) is the most common primary tauopathy, with a constellation of pathological features including 4R‐tau positive neurofibrillary tangles and tufted astrocytes. Most PSP cases are sporadic and associated with common structural variation in the 17q21.31 MAPT locus as well as other loci, including EIF2AK...
Alternative Titles
Full title
Neuropathologic and transcriptomic analysis reveals abnormal stress response in sporadic progressive supranuclear palsy autopsy brain tissue and human iPSC‐derived midbrain organoids
Authors, Artists and Contributors
Author / Creator
Krassner, Margaret M.
Selecky, Grace A.
Dangoor, Diana K.
De Sanctis, Claudia
Almazan, Victoria Flores
Cervera, Alessandra
Delica, Sean Thomas
Kim, SoongHo
Farrell, Kurt W.
Sharma, Abhijeet
Christie, Thomas D.
Iida, Megan A
Walsh, Hadley A.
Sarrafha, Lily
Parfitt, Gustavo
Walker, Ruth H.
Riboldi, Giulietta M.
Frucht, Steven J.
Ahfeldt, Tim
Zhang, Bin
Pereira, Ana C.
Temple, Sally
Crary, John F.
Song, Won‐min
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11709720
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11709720
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.093229
