ABCA1 rare variants interact with APOE isoforms to confer Alzheimer’s Disease risk
ABCA1 rare variants interact with APOE isoforms to confer Alzheimer’s Disease risk
About this item
Full title
Author / Creator
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
Several lines of evidence now suggest that ABCA1 plays a role in Alzheimer’s disease (AD). Rare variants on ABCA1 increased AD risk in a large genetic study, and mouse models suggest that increasing ABCA1 activity can reverse signs of AD pathology. While there is growing consensus that ABCA1 and ApoE directly interact, it is unclear h...
Alternative Titles
Full title
ABCA1 rare variants interact with APOE isoforms to confer Alzheimer’s Disease risk
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710118
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710118
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.092053
