Presynaptic mechanisms of impaired long term potentiation of lateral entorhinal cortex input to CA1...
Presynaptic mechanisms of impaired long term potentiation of lateral entorhinal cortex input to CA1 in the PS19 mouse model of tauopathy
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Hoboken: John Wiley and Sons Inc
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Language
English
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Publisher
Hoboken: John Wiley and Sons Inc
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Background
How tauopathy disrupts direct entorhinal cortex (EC) inputs to CA1 and their plasticity is understudied, despite its critical role in memory. Moreover, dysfunction of lateral EC (LEC) input is less clear, despite its relevance to early Alzheimer’s disease pathogenesis. Here we examined how tau impacts long‐term potentiation (LTP) of L...
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Full title
Presynaptic mechanisms of impaired long term potentiation of lateral entorhinal cortex input to CA1 in the PS19 mouse model of tauopathy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710336
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710336
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ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.086703