Rare genetic variation in fibronectin 1 (FN1) protects against APOE ɛ4 in Alzheimer’s Disease
Rare genetic variation in fibronectin 1 (FN1) protects against APOE ɛ4 in Alzheimer’s Disease
About this item
Full title
Author / Creator
Bhattarai, Prabesh , Gunasekaran, Tamil Iniyan , Uzrek, Bengisu Turgutalp , Reyes‐Dumeyer, Dolly , Jülich, Dörthe , Lee, Annie J. , Yilmaz, Elanur , Tayran, Huseyin , Lantigua, Rafael A. , Medrano, Martin , Mejia, Diones Rivera , Recio, Patricia , Flaherty, Delaney , Dalgard, Clifton L. , Nuriel, Tal , Ertekin‐Taner, Nilüfer , Dickson, Dennis W. , Teich, Andrew F , Holley, Scott , Mayeux, Richard , Kizil, Caghan and Vardarajan, Badri N.
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
APOEε4 significantly increases the risk of developing Alzheimer’s disease (AD). Cognitively healthy APOEε4‐carriers exist, suggesting potential protective mechanisms against APOEε4. We hypothesized that some APOEε4‐carriers may have genetic variations protecting them from developing APOEε4‐mediated AD pathology. We aim to identify the...
Alternative Titles
Full title
Rare genetic variation in fibronectin 1 (FN1) protects against APOE ɛ4 in Alzheimer’s Disease
Authors, Artists and Contributors
Author / Creator
Gunasekaran, Tamil Iniyan
Uzrek, Bengisu Turgutalp
Reyes‐Dumeyer, Dolly
Jülich, Dörthe
Lee, Annie J.
Yilmaz, Elanur
Tayran, Huseyin
Lantigua, Rafael A.
Medrano, Martin
Mejia, Diones Rivera
Recio, Patricia
Flaherty, Delaney
Dalgard, Clifton L.
Nuriel, Tal
Ertekin‐Taner, Nilüfer
Dickson, Dennis W.
Teich, Andrew F
Holley, Scott
Mayeux, Richard
Kizil, Caghan
Vardarajan, Badri N.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710415
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710415
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.089111
