Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s...
Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s disease: rs3851179 links to PICALM not EED
About this item
Full title
Author / Creator
Wang, Liyong , Xu, Wanying , Rajabli, Farid , Celis, Katrina , Lu, Leina , Gearing, Marla , Bennett, David A. , Flanagan, Margaret E , Weintraub, Sandra , Geula, Changiz , Schuck, Theresa , Scott, William K. , Dykxhoorn, Derek M. , Griswold, Anthony J. , Pericak‐Vance, Margaret A. , Young, Juan I , Jin, Fulai and Vance, Jeffery M.
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
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More information
Scope and Contents
Contents
Background
Annotation of target genes of non‐coding GWAS loci remains a challenge since 1) regulatory elements identified by GWAS can be metabases away from its actual target, 2) one regulatory element can target multiple genes, and 3) multiple regulatory elements can target one gene. AD GWAS in populations with different ancestries have identif...
Alternative Titles
Full title
Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s disease: rs3851179 links to PICALM not EED
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710420
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710420
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.092337