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Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s...

Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710420

Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s disease: rs3851179 links to PICALM not EED

About this item

Full title

Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s disease: rs3851179 links to PICALM not EED

Publisher

Hoboken: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2024-12, Vol.20 (S1), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley and Sons Inc

Subjects

More information

Scope and Contents

Contents

Background
Annotation of target genes of non‐coding GWAS loci remains a challenge since 1) regulatory elements identified by GWAS can be metabases away from its actual target, 2) one regulatory element can target multiple genes, and 3) multiple regulatory elements can target one gene. AD GWAS in populations with different ancestries have identif...

Alternative Titles

Full title

Harnessing chromatin loops to identify susceptibility genes in different populations for Alzheimer’s disease: rs3851179 links to PICALM not EED

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710420

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710420

Other Identifiers

ISSN

1552-5260

E-ISSN

1552-5279

DOI

10.1002/alz.092337

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