Site‐specific hyperphosphorylation of tau and C‐terminal alteration of PP2A catalytic subunit in tau...
Site‐specific hyperphosphorylation of tau and C‐terminal alteration of PP2A catalytic subunit in tau pathogenesis seeded by proteopathic tau
About this item
Full title
Author / Creator
Liu, Fei , Gu, Jianlan , Zhou, Yan , Hu, Wen , Wu, Ruozhen , Tung, Yunn Chyn , Gong, Cheng‐Xin and Iqbal, Khalid
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
Regional distribution of neurofibrillary tangles consisting of hyperphosphorylated tau correlates strongly with the progression of Alzheimer’s disease (AD). Misfolded proteopathic tau templates the conversion of naive tau into a pathological state in a prion‐like fashion, which underlies the spreading of tau pathology in the brain. Wh...
Alternative Titles
Full title
Site‐specific hyperphosphorylation of tau and C‐terminal alteration of PP2A catalytic subunit in tau pathogenesis seeded by proteopathic tau
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713030
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713030
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.094789
