Active immunotherapy, ACI‐24.060, induces anti‐Abeta antibodies with binding profiles mirroring clin...
Active immunotherapy, ACI‐24.060, induces anti‐Abeta antibodies with binding profiles mirroring clinically validated monoclonal antibodies
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Author / Creator
Fiorini, Emma , Babolin, Chiara , Carpintero, Rakel , Rigotti, Stefania , Siegert, Stefanie , Morici, Catherine , Balachandiran, Harishini , Wagg, Jonathan , Fournier, Nicolas , Herriott, Lara , Donati, Piergiorgio , Delpretti, Saskia , Mendonca, Nuno , Pfeifer, Andrea , Derouazi, Madiha , Kosco‐Vilbois, Marie and Vukicevic, Marija
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
The key advantage of active immunization is the induction of sustained, polyclonal antibody responses that are readily boosted by occasional immunizations. Recent clinical trial outcomes for monoclonal antibodies lecanemab and donanemab, establish the relevance of targeting pathological Abeta for clearing amyloid plaques in Alzheimer’...
Alternative Titles
Full title
Active immunotherapy, ACI‐24.060, induces anti‐Abeta antibodies with binding profiles mirroring clinically validated monoclonal antibodies
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713172
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.089036
