The Fetal Environment and the Development of Hypertension—The Epigenetic Modification by Glucocortic...
The Fetal Environment and the Development of Hypertension—The Epigenetic Modification by Glucocorticoids
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Intrauterine growth restriction (IUGR) is a risk factor for postnatal cardiovascular, metabolic, and psychiatric disorders. In most IUGR models, placental dysfunction that causes reduced 11β-hydroxysteroid dehydrogenase 2 (11βHSD2) activity, which degrades glucocorticoids (GCs) in the placenta, resulting in fetal GC overexposure. This overexposure...
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Full title
The Fetal Environment and the Development of Hypertension—The Epigenetic Modification by Glucocorticoids
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11720225
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11720225
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms26010420
