Rapid response of lichen planus to baricitinib associated with suppression of cytotoxic CXCL13+CD8+...
Rapid response of lichen planus to baricitinib associated with suppression of cytotoxic CXCL13+CD8+ T cells
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Author / Creator
Hwang, Angelina S , Kechter, Jacob A , Do, Tran H , Hughes, Alysia N , Zhang, Nan , Li, Xing , Bogle, Rachael , Brumfiel, Caitlin M , Patel, Meera H , Boudreaux, Blake , Bhullar, Puneet , Nassir, Shams , Yousif, Miranda L , Stockard, Alyssa L , Leibovit-Reiben, Zachary , Ogbaudu, Ewoma , DiCaudo, David J , Fox, Jennifer , Gharaee-Kermani, Mehrnaz , Xing, Xianying , Zunich, Samantha , Branch, Emily , Kahlenberg, J Michelle , Billi, Allison C , Plazyo, Olesya , Tsoi, Lam C , Pittelkow, Mark R , Gudjonsson, Johann E and Mangold, Aaron R
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
BACKGROUNDCutaneous lichen planus (LP) is a recalcitrant, difficult-to-treat, inflammatory skin disease characterized by pruritic, flat-topped, violaceous papules on the skin. Baricitinib is an oral Janus kinase (JAK) 1/2 inhibitor that interrupts the signaling pathway of IFN-γ, a cytokine implicated in the pathogenesis of LP.METHODSIn this phase I...
Alternative Titles
Full title
Rapid response of lichen planus to baricitinib associated with suppression of cytotoxic CXCL13+CD8+ T cells
Authors, Artists and Contributors
Author / Creator
Kechter, Jacob A
Do, Tran H
Hughes, Alysia N
Zhang, Nan
Li, Xing
Bogle, Rachael
Brumfiel, Caitlin M
Patel, Meera H
Boudreaux, Blake
Bhullar, Puneet
Nassir, Shams
Yousif, Miranda L
Stockard, Alyssa L
Leibovit-Reiben, Zachary
Ogbaudu, Ewoma
DiCaudo, David J
Fox, Jennifer
Gharaee-Kermani, Mehrnaz
Xing, Xianying
Zunich, Samantha
Branch, Emily
Kahlenberg, J Michelle
Billi, Allison C
Plazyo, Olesya
Tsoi, Lam C
Pittelkow, Mark R
Gudjonsson, Johann E
Mangold, Aaron R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735091
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735091
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI179436
