Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models
Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models
About this item
Full title
Author / Creator
Li, Dezhi , Geng, Ke , Hao, Yuan , Gu, Jiajia , Kumar, Saurav , Olson, Annabel T. , Kuismi, Christina C. , Kim, Hye Mi , Pan, Yuanwang , Sherman, Fiona , Williams, Asia M. , Li, Yiting , Li, Fei , Chen, Ting , Thakurdin, Cassandra , Ranieri, Michela , Meynardie, Mary , Levin, Daniel S. , Stephens, Janaye , Chafitz, Alison , Chen, Joy , Donald-Paladino, Mia S. , Powell, Jaylen M. , Zhang, Ze-Yan , Chen, Wei , Ploszaj, Magdalena , Han, Han , Gu, Shengqing Stan , Zhang, Tinghu , Hu, Baoli , Nacev, Benjamin A. , Kaiza, Medard Ernest , Berger, Alice H. , Wang, Xuerui , Li, Jing , Sun, Xuejiao , Liu, Yang , Zhang, Xiaoyang , Bruno, Tullia C. , Gray, Nathanael S. , Nabet, Behnam , Wong, Kwok-Kin and Zhang, Hua
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most frequently mutated oncogene in lung adenocarcinoma, with G12C and G12V being the most predominant forms. Recent breakthroughs in KRASG12C inhibitors have transformed the clinical management of patients with the G12C mutation and advanced our understanding of the function of this mutation...
Alternative Titles
Full title
Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models
Authors, Artists and Contributors
Author / Creator
Geng, Ke
Hao, Yuan
Gu, Jiajia
Kumar, Saurav
Olson, Annabel T.
Kuismi, Christina C.
Kim, Hye Mi
Pan, Yuanwang
Sherman, Fiona
Williams, Asia M.
Li, Yiting
Li, Fei
Chen, Ting
Thakurdin, Cassandra
Ranieri, Michela
Meynardie, Mary
Levin, Daniel S.
Stephens, Janaye
Chafitz, Alison
Chen, Joy
Donald-Paladino, Mia S.
Powell, Jaylen M.
Zhang, Ze-Yan
Chen, Wei
Ploszaj, Magdalena
Han, Han
Gu, Shengqing Stan
Zhang, Tinghu
Hu, Baoli
Nacev, Benjamin A.
Kaiza, Medard Ernest
Berger, Alice H.
Wang, Xuerui
Li, Jing
Sun, Xuejiao
Liu, Yang
Zhang, Xiaoyang
Bruno, Tullia C.
Gray, Nathanael S.
Nabet, Behnam
Wong, Kwok-Kin
Zhang, Hua
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735103
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735103
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI174249
