A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy
A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
To identify the differences between aged and young human hematopoiesis, we performed a direct comparison of aged and young human hematopoietic stem and progenitor cells (HSPCs). Alterations in transcriptome profiles upon aging between humans and mice were then compared. Human specimens consist of CD34+ cells from bone marrow, and mouse specimens of...
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Full title
A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11766015
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11766015
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms26020787
