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Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example o...

Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11780581

Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions

About this item

Full title

Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions

Publisher

England: BMJ Publishing Group Ltd

Journal title

BMJ case reports, 2025-01, Vol.18 (1), p.e261648

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

A middle childhood boy with epilepsy exhibited persistent low concentrations of valproic acid, lamotrigine and topiramate for over 1 month, primarily due to pharmacokinetic interactions involving fosphenytoin, meropenem and phenobarbital. Awareness of these clinically significant interactions is crucial for ensuring effective seizure control. Howev...

Alternative Titles

Full title

Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11780581

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11780581

Other Identifiers

ISSN

1757-790X

E-ISSN

1757-790X

DOI

10.1136/bcr-2024-261648

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