Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong...
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life
About this item
Full title
Author / Creator
Guo, Yingyu , Sun, Tianhan , Li, Mengyao , Chen, Ziwei , Liu, Ye , Luo, Xuanmei , Chen, Yuan , Li, Yayu , Kuai, Lu , Yu, Xue and Zou, Lihui
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
Purpose
Recombinant human B-type natriuretic peptide (rhBNP) has been extensively proven to be an effective mean of heart failure (HF) therapy, but its clinical application is limited by its very short half-life. This study aims to combine
in vitro
transcribed mRNA (IVT mRNA) and fusion protein technology to develop a rhBNP-Fc mRNA drug wi...
Alternative Titles
Full title
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11785693
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11785693
Other Identifiers
ISSN
0724-8741,1573-904X
E-ISSN
1573-904X
DOI
10.1007/s11095-024-03807-x
