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Immune Resistance in Glioblastoma: Understanding the Barriers to ICI and CAR-T Cell Therapy

Immune Resistance in Glioblastoma: Understanding the Barriers to ICI and CAR-T Cell Therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11816167

Immune Resistance in Glioblastoma: Understanding the Barriers to ICI and CAR-T Cell Therapy

About this item

Full title

Immune Resistance in Glioblastoma: Understanding the Barriers to ICI and CAR-T Cell Therapy

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2025-01, Vol.17 (3), p.462

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Glioblastoma (GBM) is the most common primary malignant brain tumor, with fewer than 5% of patients surviving five years after diagnosis. The introduction of immune checkpoint inhibitors (ICIs), followed by chimeric antigen receptor (CAR) T-cell therapy, marked major advancements in oncology. Despite demonstrating efficacy in other blood and solid...

Alternative Titles

Full title

Immune Resistance in Glioblastoma: Understanding the Barriers to ICI and CAR-T Cell Therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11816167

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11816167

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers17030462

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