Regulation of TTN as a mechanism of and treatment for heart failure
Regulation of TTN as a mechanism of and treatment for heart failure
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United States: American Society for Clinical Investigation
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English
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United States: American Society for Clinical Investigation
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Contents
Truncation variants in the gene TTN encoding titin are the most common cause of familial dilated cardiomyopathy (DCM), with both haploinsufficiency and "poison peptide" implicated as contributory mechanisms of disease. In this issue of the JCI, Kim et al. identify a highly conserved enhancer element approximately 500 bp downstream of the transcript...
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Full title
Regulation of TTN as a mechanism of and treatment for heart failure
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11827840
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11827840
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI189335
