Microglia internalize tau monomers and fibrils using distinct receptors but similar mechanisms
Microglia internalize tau monomers and fibrils using distinct receptors but similar mechanisms
About this item
Full title
Author / Creator
Publisher
United States: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
INTRODUCTION
Alzheimer's disease (AD) and other tauopathies are characterized by intracellular aggregates of microtubule‐associated protein tau that are actively released and promote proteopathic spread. Microglia engulf pathological proteins, but how they endocytose tau is unknown.
METHODS
We measured endocytosis of different tau species...
Alternative Titles
Full title
Microglia internalize tau monomers and fibrils using distinct receptors but similar mechanisms
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11848386
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11848386
Other Identifiers
ISSN
1552-5260,1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.14418
