The Impact of Klotho in Cancer: From Development and Progression to Therapeutic Potential
The Impact of Klotho in Cancer: From Development and Progression to Therapeutic Potential
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Author / Creator
Ortega, Miguel A , Boaru, Diego Liviu , De Leon-Oliva, Diego , De Castro-Martinez, Patricia , Minaya-Bravo, Ana M , Casanova-Martín, Carlos , Barrena-Blázquez, Silvestra , Garcia-Montero, Cielo , Fraile-Martinez, Oscar , Lopez-Gonzalez, Laura , Saez, Miguel A , Alvarez-Mon, Melchor and Diaz-Pedrero, Raul
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Klotho, initially identified as an anti-aging gene, has been shown to play significant roles in cancer biology. Alongside α-Klotho, the β-Klotho and γ-Klotho isoforms have also been studied; these studies showed that Klotho functions as a potential tumor suppressor in many different cancers by inhibiting cancer cell proliferation, inducing apoptosi...
Alternative Titles
Full title
The Impact of Klotho in Cancer: From Development and Progression to Therapeutic Potential
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11854833
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11854833
Other Identifiers
ISSN
2073-4425
E-ISSN
2073-4425
DOI
10.3390/genes16020128
