The Noncanonical Wnt5a–Ca2+ Pathway Mediates Mitochondrial Dysfunction in the Progression of Diabeti...
The Noncanonical Wnt5a–Ca2+ Pathway Mediates Mitochondrial Dysfunction in the Progression of Diabetic Nephropathy via the Mitochondrial Calcium Uniporter
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Author / Creator
Fei, Yang , Zhang, Qunzi , Jia, Junjie , He, Li , Gu, Sijie , Cheng, Dongsheng , Lin, Wenjun , Xing, Haifan , Wang, Niansong and Fan, Ying
Publisher
Chichester: John Wiley & Sons, Inc
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Language
English
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Publisher
Chichester: John Wiley & Sons, Inc
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ABSTRACT
Abnormal Wnt5a expression, mitochondrial abnormalities and calcium overload have been detected in many metabolic diseases. However, the association of Wnt5a–Ca2+ and mitochondrial dysfunction in diabetic nephropathy (DN) progression remains unknown. We used streptozotocin‐induced DBA2/J male mice as a DN model. The mice were treated wit...
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Full title
The Noncanonical Wnt5a–Ca2+ Pathway Mediates Mitochondrial Dysfunction in the Progression of Diabetic Nephropathy via the Mitochondrial Calcium Uniporter
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11862900
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11862900
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ISSN
1582-1838,1582-4934
E-ISSN
1582-4934
DOI
10.1111/jcmm.70422