The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor
The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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I3MT-3 (HMPSNE) has been identified as a selective inhibitor of the supersulfide-producing enzyme 3-MST. In this study, we found that I3MT-3 inhibits inflammatory responses, including the secretion of the pro-inflammatory cytokine interleukin-1β (IL-1β) and inflammatory cell death pyroptosis, induced by the activation of the inflammasomes composed...
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The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11899812
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11899812
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms26052237
