Exosome‐Mediated Lectin Pathway and Resistin‐MIF‐AA Metabolism Axis Drive Immune Dysfunction in Immu...
Exosome‐Mediated Lectin Pathway and Resistin‐MIF‐AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia (Adv. Sci. 10/2025)
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Author / Creator
Li, Jin , Wang, Xiaoqian , Chen, Yaoyao , Sun, Xianlei , Fu, Liyan , Xin, Qingxuan , Zhang, Huilin , Qin, Bo , Sun, Nannan , Li, Yingmei , Xu, Yan , Yang, Hui , Huo, Dawei , Dong, Yong , Wang, Shuya , Zhao, Mengyun , Lin, Quande , Wang, Fang , Yue, Baohong , Gao, Yanxia , Jiang, Yong and Guo, Rongqun
Publisher
Weinheim: John Wiley & Sons, Inc
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English
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Weinheim: John Wiley & Sons, Inc
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Immune Thrombocytopenia
The exosomes from patients with immune thrombocytopenia induce complement system activation through delivery of FCN2 and MBL2, triggering platelet destruction and hyperactivation of immune cells. The hyperactivated immune cells exploit resistin, MIF and arachidonic acid metabolism to enforce aberrant immune responses‐ aki...
Alternative Titles
Full title
Exosome‐Mediated Lectin Pathway and Resistin‐MIF‐AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia (Adv. Sci. 10/2025)
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11904964
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11904964
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202570066
