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RNase L represses hair follicle regeneration through altered innate immune signaling

RNase L represses hair follicle regeneration through altered innate immune signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11910212

RNase L represses hair follicle regeneration through altered innate immune signaling

About this item

Full title

RNase L represses hair follicle regeneration through altered innate immune signaling

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2025-03, Vol.135 (6), p.1-18

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Mammalian injury responses are predominantly characterized by fibrosis and scarring rather than functional regeneration. This limited regenerative capacity in mammals could reflect a loss of proregeneration programs or active suppression by genes functioning akin to tumor suppressors. To uncover programs governing regeneration in mammals, we screen...

Alternative Titles

Full title

RNase L represses hair follicle regeneration through altered innate immune signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11910212

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11910212

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI172595

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