Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and...
Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and cold-induced lipolysis
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Author / Creator
Yeh, Yu-Sheng , Evans, Trent D. , Iwase, Mari , Jeong, Se-Jin , Zhang, Xiangyu , Liu, Ziyang , Park, Arick , Ghasemian, Ali , Dianati, Borna , Javaheri, Ali , Kratky, Dagmar , Kawarasaki, Satoko , Goto, Tsuyoshi , Zhang, Hanrui , Dutta, Partha , Schopfer, Francisco J. , Straub, Adam C. , Cho, Jaehyung , Lodhi, Irfan J. and Razani, Babak
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Adipose tissue lipolysis is the process by which triglycerides in lipid stores are hydrolyzed into free fatty acids (FFAs), serving as fuel during fasting or cold-induced thermogenesis. Although cytosolic lipases are considered the predominant mechanism of liberating FFAs, lipolysis also occurs in lysosomes via lysosomal acid lipase (LIPA), albeit...
Alternative Titles
Full title
Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and cold-induced lipolysis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11910232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11910232
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI185340
