MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregul...
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction
About this item
Full title
Author / Creator
Zhou, Huijun , Gong, Han , Zeng, Xiaohui , Zeng, Chong , Liu, Dian , Liu, Jie and Zhang, Yingying
Publisher
D.A. Spandidos
Journal title
Language
English
Formats
Publication information
Publisher
D.A. Spandidos
More information
Scope and Contents
Contents
One-carbon metabolism plays an important role in cancer progression. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial enzyme in one-carbon metabolism, is dysregulated in several cancer types. However, the precise role and mechanisms of MTHFD2 in esophageal squamous cell carcinoma (ESCC) remain unclear. The present study unravels...
Alternative Titles
Full title
MTHFD2 promotes esophageal squamous cell carcinoma progression via m6A modification‑mediated upregulation and modulation of the PEBP1‑RAF1 interaction
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11913433
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11913433
Other Identifiers
ISSN
1107-3756
E-ISSN
1791-244X
DOI
10.3892/ijmm.2025.5509
