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Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma

Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11974838

Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma

About this item

Full title

Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma

Publisher

United States: Cold Spring Harbor Laboratory

Journal title

bioRxiv, 2025-03

Language

English

Formats

Publication information

Publisher

United States: Cold Spring Harbor Laboratory

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Neuroblastoma is a heterogeneous malignant paediatric tumor with prognosis depending on patient age and disease stage. Current treatment strategies rely on four key diagnostic criteria: age, histological stage,
gene status, and genomic profile. It has been reported that MYC oncogenic activity depends on ribosome biogenesis, whose hyperactivation...

Alternative Titles

Full title

Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11974838

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11974838

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2025.03.26.645392

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