Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma
Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma
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Publisher
United States: Cold Spring Harbor Laboratory
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory
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Contents
Neuroblastoma is a heterogeneous malignant paediatric tumor with prognosis depending on patient age and disease stage. Current treatment strategies rely on four key diagnostic criteria: age, histological stage,
gene status, and genomic profile. It has been reported that MYC oncogenic activity depends on ribosome biogenesis, whose hyperactivation...
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Full title
Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11974838
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11974838
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2025.03.26.645392