PGLYRP2 drives hepatocyte-intrinsic innate immunity by trapping and clearing hepatitis B virus
PGLYRP2 drives hepatocyte-intrinsic innate immunity by trapping and clearing hepatitis B virus
About this item
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Author / Creator
Li, Ying , Ma, Huihui , Zhang, Yongjian , He, Tinghui , Li, Binyang , Ren, Haoran , Feng, Jia , Sheng, Jie , Li, Kai , Qian, Yu , Wang, Yunfeng , Zhao, Haoran , He, Jie , Li, Huicheng , Wu, Hongjin , Yao, Yuanfei and Shi, Ming
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Spontaneous clearance of hepatitis B virus (HBV) is frequent in adults (95%) but rare in infants (5%), emphasizing the critical role of age-related hepatic immunocompetence. However, the underlying mechanisms of hepatocyte-specific immunosurveillance and age-dependent HBV clearance remain unclear. Here, we identified PGLYRP2 as a hepatocyte-specifi...
Alternative Titles
Full title
PGLYRP2 drives hepatocyte-intrinsic innate immunity by trapping and clearing hepatitis B virus
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11996887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11996887
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI188083
