Cucurbitacin B Exhibits Antitumor Effects on Chordoma Cells via Disruption of Brachyury
Cucurbitacin B Exhibits Antitumor Effects on Chordoma Cells via Disruption of Brachyury
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Chordomas are rare malignant tumors of the bone, originating from remnants of notochordal cells. The transcription factor brachyury, encoded by TBXT, serves as a critical diagnostic marker and is essential for tumor growth. While brachyury’s role in regulating the cytoskeleton during embryogenesis and tumorigenesis is well understood, the reverse—w...
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Cucurbitacin B Exhibits Antitumor Effects on Chordoma Cells via Disruption of Brachyury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12028342
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12028342
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms26083864
