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Intestinal Activation of LXRα Counteracts Metabolic-Associated Steatohepatitis Features in Mice

Intestinal Activation of LXRα Counteracts Metabolic-Associated Steatohepatitis Features in Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12030714

Intestinal Activation of LXRα Counteracts Metabolic-Associated Steatohepatitis Features in Mice

About this item

Full title

Intestinal Activation of LXRα Counteracts Metabolic-Associated Steatohepatitis Features in Mice

Publisher

Switzerland: MDPI AG

Journal title

Nutrients, 2025-04, Vol.17 (8), p.1349

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Background/Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health problem and the discovery of drugs is challenging. In this study, we aimed to investigate the effects of intestinal activation of the liver X receptor (LXR)α on MASH. Methods: An intestinal-specific LXRα activation model in mice was es...

Alternative Titles

Full title

Intestinal Activation of LXRα Counteracts Metabolic-Associated Steatohepatitis Features in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12030714

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12030714

Other Identifiers

ISSN

2072-6643

E-ISSN

2072-6643

DOI

10.3390/nu17081349

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