Log in to save to my catalogue

Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with...

Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12052211

Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid

About this item

Full title

Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2025-04, Vol.23 (4), p.e3003080

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Panton-Valentine leukocidin (PVL) is a pore-forming toxin secreted by Staphylococcus aureus strains that cause severe infections. Bicomponent PVL kills phagocytes depending on cell surface receptors, such as complement 5a receptor 1 (C5aR1). How the PVL-receptor interaction enables assembly of the leukocidin complex, targeting of membranes, and ins...

Alternative Titles

Full title

Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12052211

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12052211

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3003080

How to access this item