Utility of the Base Editing System for Introducing Drug-Resistant Gene Mutations Into Human Leukemia...
Utility of the Base Editing System for Introducing Drug-Resistant Gene Mutations Into Human Leukemia Cellular Models
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United States: Springer Nature B.V
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English
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United States: Springer Nature B.V
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Background Recent genomic analyses of poor prognostic and relapsed leukemia have revealed the involvement of diverse gene mutations in treatment resistance. These gene mutations are classified into two groups: mutations involving resistance to specific agents such as the
fusion gene mutations (typically T315I mutation) in tyrosine kinase inhib...
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Utility of the Base Editing System for Introducing Drug-Resistant Gene Mutations Into Human Leukemia Cellular Models
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12060998
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12060998
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ISSN
2168-8184
E-ISSN
2168-8184
DOI
10.7759/cureus.81889
