Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy
Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy
About this item
Full title
Author / Creator
Prakash, Sindhuri , Steers, Nicholas J. , Li, Yifu , Sanchez-Rodriguez, Elena , Verbitsky, Miguel , Robbins, Isabel , Simpson, Jenna , Pathak, Sharvari , Raska, Milan , Reily, Colin , Ng, Anna , Liang, Judy , DeMaria, Natalia , Katiraei, Amanda , Stevens, Kelsey O. , Fischman, Clara , Shapiro, Samantha , Kodali, Swetha , McCutchan, Jason , Park, Heekuk , Eliby, Djamila , Delsante, Marco , Allegri, Landino , Fiaccadori, Enrico , Bodria, Monica , Marasa, Maddalena , Raveche, Elizabeth , Julian, Bruce A. , Uhlemann, Anne-Catrin , Kiryluk, Krzysztof , Zhang, Hong , D’Agati, Vivette D. , Sanna-Cherchi, Simone , Novak, Jan and Gharavi, Ali G.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Aberrant O-glycosylation of the IgA1 hinge region is a characteristic finding in patients with IgA nephropathy (IgAN) and is thought to contribute to immune-complex formation and kidney injury. Other studies have suggested that abnormalities in mucosal immunity and lymphocyte homing are major contributors to disease. We identified a family with IgA...
Alternative Titles
Full title
Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy
Authors, Artists and Contributors
Author / Creator
Steers, Nicholas J.
Li, Yifu
Sanchez-Rodriguez, Elena
Verbitsky, Miguel
Robbins, Isabel
Simpson, Jenna
Pathak, Sharvari
Raska, Milan
Reily, Colin
Ng, Anna
Liang, Judy
DeMaria, Natalia
Katiraei, Amanda
Stevens, Kelsey O.
Fischman, Clara
Shapiro, Samantha
Kodali, Swetha
McCutchan, Jason
Park, Heekuk
Eliby, Djamila
Delsante, Marco
Allegri, Landino
Fiaccadori, Enrico
Bodria, Monica
Marasa, Maddalena
Raveche, Elizabeth
Julian, Bruce A.
Uhlemann, Anne-Catrin
Kiryluk, Krzysztof
Zhang, Hong
D’Agati, Vivette D.
Sanna-Cherchi, Simone
Novak, Jan
Gharavi, Ali G.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12077892
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12077892
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI181164
