Depletion-dependent activity-based protein profiling using SWATH/DIA-MS detects serine hydrolase lip...
Depletion-dependent activity-based protein profiling using SWATH/DIA-MS detects serine hydrolase lipid remodeling in lung adenocarcinoma progression
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Systematic inference of enzyme activity in human tumors is key to understanding cancer progression and resistance to therapy. However, standard protein or transcript abundances are blind to the activity status of the measured enzymes, regulated, for example, by active-site amino acid mutations or post-translational protein modifications. Current me...
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Depletion-dependent activity-based protein profiling using SWATH/DIA-MS detects serine hydrolase lipid remodeling in lung adenocarcinoma progression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12117057
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12117057
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-59564-x
