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Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Stre...

Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Stre...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12218379

Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Streptococcus sanguinis

About this item

Full title

Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Streptococcus sanguinis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-07, Vol.15 (1), p.22017, Article 22017

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

2-Aminoacrylate (2AA) is a short-lived enamine generated as a catalytic intermediate in the dehydration of serine by serine/threonine dehydratase enzymes. 2AA is a metabolic stressor capable of inactivating important pyridoxal phosphate dependent enzymes in a cell. Detoxification of 2AA in a cell is catalyzed by members of the Reactive intermediate...

Alternative Titles

Full title

Biochemical and structural characterization of a reactive intermediate deaminase A homolog from Streptococcus sanguinis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12218379

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12218379

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-025-05264-x

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