Newborn mitochondrial DNA copy number is associated with changes to DNA methylation that persist int...
Newborn mitochondrial DNA copy number is associated with changes to DNA methylation that persist into childhood and are associated with cognitive development
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Author / Creator
Kupsco, Allison , Heiss, Jonathan A. , Sanchez-Guerra, Marco , Estrada-Gutierrez, Guadalupe , Lesseur, Corina , Hernández, Carmen , Bloomquist, Tessa R. , Abigail, Gaylord , Guo, Jia , Wang, Shuang , Herbstman, Julie B. , Just, Allan C. , Téllez-Rojo, Martha M. , Wright, Robert O. and Baccarelli, Andrea A.
Publisher
Germany: BioMed Central Ltd
Journal title
Language
English
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Publisher
Germany: BioMed Central Ltd
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Scope and Contents
Contents
Mitochondrial-nuclear crosstalk is critical for cell function, and nuclear DNA methylation (DNAm) may regulate this process. Mitochondria maintain an extranuclear genome, and mitochondrial DNA copy number (mtDNA-CN) has been previously associated with DNAm. However, there is little information on this relationship in children, whose brains are part...
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Full title
Newborn mitochondrial DNA copy number is associated with changes to DNA methylation that persist into childhood and are associated with cognitive development
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12224777
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12224777
Other Identifiers
ISSN
1868-7083,1868-7075
E-ISSN
1868-7083
DOI
10.1186/s13148-025-01896-y
