ASXL1 truncating mutations drive leukemic resistance to T cell attack
ASXL1 truncating mutations drive leukemic resistance to T cell attack
About this item
Full title
Author / Creator
McCurry, Dustin , Ge, Zhongqi , Lee, Jaehyun , Pasumarthi, Rishi , Leng, Xiaohong , Koehnke, Thomas , Pasvolsky, Oren , Raparla, Pranaya , Nguyen, Vinhkhang , Maurer, Katie , Li, Shuqiang , Livak, Kenneth J , Danson, Emerie , Thakkar, Bijal , Azizi, Elham , Soiffer, Robert J , Shukla, Sachet A , Majeti, Ravi , Ritz, Jerome , Wu, Catherine J , Molldrem, Jeffrey J and Bachireddy, Pavan
Publisher
United States: Cold Spring Harbor Laboratory
Journal title
Language
English
Formats
Publication information
Publisher
United States: Cold Spring Harbor Laboratory
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More information
Scope and Contents
Contents
We previously found that specific exhausted T cell subsets defined response, but not resistance, to donor lymphocyte infusions (DLI), a curative immunotherapy for leukemic relapse following allogeneic stem cell transplant (SCT). To identify leukemia molecular pathways that drive resistance, we analyzed whole exome and targeted mutation panel sequen...
Alternative Titles
Full title
ASXL1 truncating mutations drive leukemic resistance to T cell attack
Authors, Artists and Contributors
Author / Creator
Ge, Zhongqi
Lee, Jaehyun
Pasumarthi, Rishi
Leng, Xiaohong
Koehnke, Thomas
Pasvolsky, Oren
Raparla, Pranaya
Nguyen, Vinhkhang
Maurer, Katie
Li, Shuqiang
Livak, Kenneth J
Danson, Emerie
Thakkar, Bijal
Azizi, Elham
Soiffer, Robert J
Shukla, Sachet A
Majeti, Ravi
Ritz, Jerome
Wu, Catherine J
Molldrem, Jeffrey J
Bachireddy, Pavan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12258899
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_12258899
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2025.05.29.656798
