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Human skin cells support thymus-independent T cell development

Human skin cells support thymus-independent T cell development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1253623

Human skin cells support thymus-independent T cell development

About this item

Full title

Human skin cells support thymus-independent T cell development

Author / Creator

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2005-11, Vol.115 (11), p.3239-3249

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Thymic tissue has previously been considered a requirement for the generation of a functional and diverse population of human T cells. We report that fibroblasts and keratinocytes from human skin arrayed on a synthetic 3-dimensional matrix support the development of functional human T cells from hematopoietic precursor cells in the absence of thymi...

Alternative Titles

Full title

Human skin cells support thymus-independent T cell development

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1253623

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1253623

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI24731

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